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#Know more Science

A1c as a key reference
HbA1c or A1c, also known as glycated hemoglobin, is a globally recognized indicator of blood sugar levels and diabetes risk.
Most scientific publications define pre-diabetes above 5.7% and diabetes at levels above 6.5%.
What is the risk not to self-control and keep A1C below 6.5%?
The vast majority of people with T2D have A1C above 7%
Then sadly 1 person die from diabetes or complication of diabetes every 15 seconds.
Why can I not detect diabetes easily?
The Sugar, a silent killer.
Because the symptoms progress slowly over 15 years. By the time most people are diagnosed, it is hard to reverse.
This means that over time, the body’s cells have more and more difficulty using the insulin made by the Pancreas
The Pancreas compensates by making more and more insulin.
Cells in the Liver also become damaged
As pancreas declines and sugars rise, the condition called “Pre-Diabetes” sets in
Multiple publications show that Fasting glycemia between 100mg/dl and 125mg/dl* indicates you have pre-diabetes*
Without intervention, medication is needed to control blood sugar. Eventually the Pancreas loses
See Fig 1 & Fig 2
What causes Type-2 diabetes?
Most cases of Type-2 are caused by poor lifestyle choices (diet/exercise).
  • Lifestyle Choices
  • Too many carbohydrates in diet (especially high-glycemic index foods)
  • Not enough exercise (cardio and strength training)
  • Too much stress
  • A small percentage of T2D cases are the result of heredity. However, even if it is caused by your genes you may still get significant benefit from improving your lifestyle (food/exercise). LipsTech can help you achieve your goals.
    Why most of people do not monitor their glucose today?
    Lack of clear symptoms and a T2D diagnosis, Glucose fluctuates throughout the day, so frequent monitoring is needed
    Glucose monitors typically rely on finger-sticks and needles.
    Scheduling a lab blood test for A1c is time consuming and expensive.
    How does glucose affect the body?
    When your glucose is high for a prolonged time, your red-blood cells become "brittle" and can shred the tiny capilaries that feed oxygenated blood to your organs.
    This can produce severe problems in organs such as the liver, your eyes and your extremeties (fingers, feet, etc).
    When you consume quantities of carbohydrates, your blood sugar will spike. Eventually the pancreas will generate enough insulin to compensate, but frequently it will over produce, leading to a drop in glucose. You then feel hungry, leading to over eating - and repeating the cycle. Using the LipsTech system will help you to avoid this behavior and revese the progression to full T2D
    See Fig 3 below
    How long does it take for home delivery?
    We use Royal mail and DHL to send most of our UK orders.Euro Car Parts reserves the right to use discretion in any circumstance where it makes more sense to use an alternative delivery method.
    Is it usable by overweight kids or gestational diabetes women?
    Our product is not a medical device but it can help people to evaluate their level of glucose and motivate them to react thanks to the real time color green/orange/red feedback & coaching inside our smartphone App . (reminder that estimated glucose values appear 2h later & A1C after 1 week of data).
    60 Years of Scientific insights: Shaping the future of Biosensor
    LipsTech draws on six decades of scientific research and publications, Backed by a team with decades of experience in biosensors and diabetes.
    We have meticulously analyzed over 100 studies spanning 60 years of global scientific research on saliva-based diagnostics.
    Our commitment extends beyond analysis; we will continuously conduct pre-clinical tests and clinical trials to validate every scientific aspect.
    Global R&D Related to Covid-19 Boosted Saliva Technology
    Over two decades of tireless global collaboration and research have culminated in the maturation of our technology.
    The Recent emergence of COVID-19 has propelled saliva-based biosensors into the spotlight, benefiting from breakthrough technologies that have overcome previously insurmountable barriers.
    With recent breakthroughs in nanotechnology and bioengineering, our patented technologies allow accurate measurement of activity & health related biomarkers in small amounts of saliva.
    Technology & 97% Accuracy
    Leveraging disruptive nanomaterials and advanced Continuous Glucose Monitoring (CGM) biosensor technology, we have developed an accurate and reusable saliva-based monitoring device.
    It boasts over 97% accuracy, based on a scientific study conducted on 100 individuals, with over 60 tests each.
    LCD sreen and Encryption : why?
    A large majority of T2D diabetics are over 70 years old, not always comfortable with technology and Bluetooth synchronization to their phone. As a result, 70% of these people do not connect their Bluetooth SBGM to their phone. It therefore seemed essential to us to provide results directly on the product, independent of a smartphone app.
    Thus, after each test, the screen will indicate the glucose test result with a colored circle (green/orange/red), as well as the number of tests and days remaining, the updated A1C level, and the remaining battery level.
    Of course, this information and more will be found in the app, such as glucose values, but delayed by 2 hours to avoid the use of insulin dosing, all with an EAL6 banking-level encryption system to prevent hacking of this data.
    1 LT Tip, 5 foams?
    The LT Tip has five foams, overall concept protected by several patents. Four upper foams and one lower foam.
    The lower foam allows to clean the sensor when the cap is closed.
    The four upper foams allow to perform four tests in a row if necessary. Each foam can only be used once per hour (this gives time for the saliva to evaporate and the foam to be sterilized).
    Our scientific studies have shown that saliva residue is minimal and does not affect subsequent results, up to 150 foam reuses.
    Any constraint with saliva?
    Saliva tests require that nothing be taken into the mouth 20 minutes before the test (brushing teeth, smoking, eating, etc.).
    Since the recommended tests are to be performed at fasting, before a meal or 20 minutes/ 2 hours after a meal, this doesn't pose any major problems.
    If you experience a dry mouth in the morning, which can happen to certain people, simply take a sip of water and saliva production will quickly resume.
    Also, if sometimes you do not collect enough saliva, the system will give you an alert (screen flash and buzzer) to signal you to take more saliva.
    Simple Goal : Be Green
    The colors on the LT device indicate the glucose level and help you to react quickly based on each separate type of measurement ( fasting, spike, meal + 2h etc), target being to be green:
    • Green All ok.
    • Orange Glucose is elevated, follow coaching advice from App, in order to come back to Green.
    • Red Glucose is high, follow App’s coaching advice . Metabolism at risk if red is repeated often within one month
    Retrain Your Metabolism Reboot Your Potential
    Healing your metabolism can have many other positive effects on your life (even within a few weeks)

    Lose weight :
    Flattening your glucose spikes will keep your Pancreas from over producing insulin and make you crave snacks less
    Sleep better :
    Steady glucose can improve your sleep, which can improve mental functioning and make it easier to stay on track with your eating goals.
    Boost your energy:
    Sugary foods are often followed by a crash (hypoglycemia). This cycle can continue all day, resulting in fatigue and a lack of energy
    Stabilize your mood :
    Getting your food consumption under control and your glucose stabilized can give you a wonderful sense of satisfaction and boost your confidence.
    Improve your focus:
    Glucose is brain fuel. Too little or too much glucose can throw off your concentration
    Why is LT Lipstick not a medical device?

    The LT Lipstick does not impact patients' medical treatment or clinical management. Its aim is to help improve users’ lifestyle as a means to reduce their risk of diabetes. It is positioned as a non-IVD product in both Europe and the USA.

    Users are recommended to confirm their glucose level using certified medical technologies (CGM, BGM, etc.) after using the Lipstick Connect.

    The risk color coding (based on estimated glucose trends like A1C) is for awareness only. Glucose values are only estimates and must be confirmed by a medical device if necessary.

    No medical decision should be made based on the output of a wellness device.

    The LT Lipstick is intended strictly for healthy lifestyle purposes. All measurements and indications are estimations and must be confirmed by a certified medical device if needed.

    How long does it take for home delivery?
    We use Royal mail and DHL to send most of our UK orders.Euro Car Parts reserves the right to use discretion in any circumstance where it makes more sense to use an alternative delivery method.
    Scientific references
    1. (2013) FHAS 2013 _OMS : Type 2 diabetes in adults care pathway guide (https://www.has-sante.fr/upload/docs/application/pdf/2014-04/guide_pds_diabete_t_3_web.pdf)
    2. (1975) Feller and Shannon: Postprandial correlation
    3. (2001) Amer - Siddiqui: Salivary glucose concentrations in diabetic patients: good correlation with blood
    4. (2008) Streedevi: Comparison of serum and salivary glucose: good correlation with blood; influence of salivary flow rate (SFR)
    5. (1998) Anderson: Lag time between saliva and blood glucose
    6. (2022) David: FDA vs Wellness – Medical device classification
    7. (2014) Kumar: Salivary glucose correlation with blood glucose levels (BGL) and HbA1c
    8. (2019) Shang: Reversible pre-type 2 diabetes
    9. (2017) L. Monnier: Coefficient of variation > 36% vs hypoglycemia
    10. (2017) Morgan Fitch: HbA1c and medication adherence
    11. (2022) Alsbrooks: 63% fear of needles vs 96% general anxiety and 70% fear of pain
    Statistical references
    1. 63% of individuals report a fear of needles (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678288/)
    2. Global diabetes prevalence: 642M by 2030 (IDF – https://diabetesatlas.org/data/en/world/), and 1.3B by 2050 (The Lancet – https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01301-6/fulltext)
    3. USA 2024: 25M with non-insulin-dependent T2D, 15M diagnosed prediabetics, ~85M undiagnosed (https://www.medtechdive.com/news/abbott-dexcom-over-the-counter-cgm-launch/719928/)
    4. Too much sugar leads to fatigue, weight gain, mood swings, digestive issues (https://www.passeportsante.net/fr/Actualites/Dossiers/DossierComplexe.aspx?doc=10-signes-consommez-trop-sucre)
    5. Type 2 diabetes has grown 50-fold since 2020 (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01301-6/fulltext)
    6. 1 in 4 U.S. healthcare dollars is spent on diabetes; estimated total cost: $327B (ADA/Dexcom, 2021)
    7. 280M obese children projected globally by 2030 (https://www.aprifel.com/fr/article-revue-equation-nutrition/obesite-infantile-prevalence-et-tendances-dans-le-monde/)
    8. 80% of obese individuals have T2D (https://www.mdpi.com/1422-0067/25/3/1882#B113-ijms-25-01882); 42% of adults obese in 2020, >50% expected by 2030 (CDC – Gemini)
    9. France: over 4M people being treated for diabetes (https://www.federationdesdiabetiques.org/information/diabete/chiffres-france), (https://www.inserm.fr/dossier/diabete-type-2/)
    10. 29% of French people are upper socio-professional class (https://fr.wikipedia.org/wiki/CSP%2B); >30% of Americans earn over $100K/year (https://atlantico.fr/article/decryptage/plus-du-tiers-des-menages-americains-a-des-revenus-superieurs-a-100-000euro-par-an-et-voila-l-impact-que-ca-aura-pour-les-europeens-philippe-crevel)
    11. 95% of diabetes cases are type 2 (https://www.federationdesdiabetiques.org/information/diabete/chiffres-monde)
    12. Obesity shortens life expectancy (https://sante.lefigaro.fr/social/sante-publique/l-esperance-de-vie-en-europe-progresse-moins-vite-depuis-2011-sauf-dans-une-poignee-de-pays-20250219)
    13. Gestational diabetes affects 6–14% of pregnancies (https://pmc.ncbi.nlm.nih.gov/articles/PMC8909680/#B7-ijerph-19-02583)
    14. Average age of T2D diagnosis is over 65 (https://www.inserm.fr/dossier/diabete-type-2/)
    15. 1 diabetes-related death every 15 seconds worldwide (https://www.who.int/fr/news-room/fact-sheets/detail/diabetes)
    16. 76% of T2D patients have HbA1c > 6.5%; 40% discontinue oral treatment after a few years (Morgan Fitch, 2017)